Jessica introduces the story in which Dennis Stanton investigates the murder of Truman Calloway, a man with no shortage of enemies, when the ex-husband of one of Calloway's clients is charged with the murder.
A journalist died before finishing his book trying to show a man was unjustly convicted of murder 16 years ago. Jessica is asked to use his notes to finish his book.
Monk's hypnotic regression to his childhood begins to affect the case on which he's consulting - an actress who's disappeared, and the holes in her story when she's found after a deadly escape.
Monk's Christmas spirit, or lack thereof, is challenged when he takes a case from three homeless men who believe their friend was murdered, and Leland's epiphany sends him on a mission.
When Monk's half-brother Jack shows up at his door, he's less than thrilled, especially after learning that Jack has just escaped from prison and is accused of killing a very popular female employee while making his escape.
Chet Brooks, one of Jack's old friends, shows up on the run from gamblers, begging for help. Jack reluctantly loans Chet his car, only to have Chet and the car explode in a fiery wreck.
A convict, being treated at County General, manages to take a hostage and demand news coverage. When the newscaster covering the event is shot down, Dr. Sloan takes it upon himself to figure out what went wrong.
A Los Angeles earthquake apparently causes an armoire to topple over on top of a good friend of Dr. Sloan's, Martin Garfield, killing him. Sloan goes to work and discovers that Garfield may have been killed before the earthquake.
A gangland 'protector' under surveillance by Steve becomes infected with the plague when a medicine bottle is mysteriously switched. Dr. Sloan tries to find the source of the virus before the murderer starts an epidemic.
The news isn't good for Matlock's TV reporter client--the real murderer turns up dead, but Matlock still has to get the scoop on the real estate scam to free him.
When a visit to a mystery-themed resort goes wrong, a local detective and a vacationing British criminal psychiatrist team up to solve a real murder. Starring Elizabeth Henstridge, Charlie Weber.
Birdie and Alden Case find a way to keep the mystery in their marriage alive, literally, when the amateur sleuths are pulled into a murder investigation. Stars Aimee Garcia, Paul Campbell.